Designed for Clinical Development Teams
The ORIGIN platform is deployed within companion animal clinical trials to replace subjective endpoints with reproducible, behavior-derived measurement.
Improves Signal Quality and Study Outcomes
The ORIGIN platform is designed for multi-site clinical trials where endpoint variability degrades statistical power.
- Lower inter-rater variability
- Higher signal-to-noise
- Stronger statistical power
- Continuous, incl. overnight
Higher temporal resolution improves endpoint fidelity, reduces measurement noise, and supports stronger statistical power.[3]
Statistics calculated from client-evaluated credibility tests against expert annotators. Specific study details withheld for client confidentiality.
Subjective Endpoints Limit Study Outcomes
Subjective endpoints introduce inter-rater variability and scoring inconsistency that degrade statistical power[1] — increasing the risk of inconclusive outcomes and delayed development timelines.
Subjective scales capture opinion. The ORIGIN platform measures behavior.
Veterinary Pruritus — Clinical Endpoint Model
The ORIGIN platform captures pruritic behaviors as continuous, structured events[2] — recording onset, duration, and offset across every observable episode with full audit traceability.
Scratching
Forelimb, hindlimb, and compound episodes captured as structured events.
Biting
Targeted biting behavior with full onset-to-offset capture.
Rubbing
Head, face, and body contact recorded as discrete behavioral events.
Head Shaking
Episode frequency and duration with structured timestamps.
Continuous behavioral measurement — every event captured from onset to offset.
Where intermittent scoring samples moments, the ORIGIN platform captures complete behavioral episodes as structured clinical data.
Designed for Existing Study Workflows
The ORIGIN platform integrates into current clinical study designs without requiring workflow redesign or infrastructure change.
What you provide
- →Standard video capture (≥1080p, fixed camera)
- →Study metadata (animal IDs, timepoints)
What the ORIGIN platform delivers
- ✓Structured clinical endpoints
- ✓Study-ready datasets within days
- ✓Scalable processing across concurrent studies
No workflow disruption.
Every endpoint is fully traceable, reproducible, and audit-ready.
Generate Clinical Endpoints in Your Next Study
Evaluate the impact of objective behavioral endpoints on your study outcomes.
References
- Plant JD. “Repeatability and reproducibility of numerical rating scales and visual analogue scales for canine pruritus severity scoring.” Veterinary Dermatology, 2007. View →
- Park I, Lee K, Bishayee K, Jeon HJ, Lee H, Lee U. “Machine-Learning Based Automatic and Real-time Detection of Mouse Scratching Behaviors.” Experimental Neurobiology, 2019. View →
- Tjandrasuwita M, Sun JJ, Chaudhuri S, Kennedy A, Yue Y. “Interpreting Expert Annotation Differences in Animal Behavior.” arXiv preprint, 2021. View →